Course Description:
Beyond bioinformatics, cells as systems. Metabolic networks, transcription regulatory networks, signaling networks. Deterministic and stochastic kinetics. Mathematical representation of reconstructed networks. Network motifs. Signal transduction and neuronal networks. Robustness. Bacterial chemotaxis and patterning in fruit fly development. Kinetic proofreading. Optimal gene circuit design. Rules for gene regulation. Random networks and multiple time scales. Biological information processing. Numerical and simulation techniques. Major project(s) in Matlab.
Faculty/Manager:
Predrag Jelenkovic
Contact Information:
Predrag Jelenkovic
email: predrag@ee.columbia.eduCredits for Course: 4.5 Viewing Schedule: 1 lecture per week Prerequisites: Introduction to Genomic Information Science and Technology (ECBM E4060) or the instructor's permission. Notes: Course Introduction